Chemical composition and biological activity of haplophyllum. Eslam elaswar 1, moustafa zahran 2 and maged elkemary 3. Home phcog j, vol 8, issue 1, janfeb, 2016 gcms analysis and potential cytotoxic activity of haplophyllum tuberculatum essential oils against lung and liver cancer cells. The structural studies on the medicinal plant haplophyllum. Lignans of haplophyllum tuberculatum sciencedirect. Chemical composition and biological activity of haplophyllum tuberculatum juss. Alkaloids from haplophyllum tuberculatum, cheminform on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Identification of chemical compounds in essential oils from. In vitro propagation and cryopreservation of native desert. Influence of haplophyllum tuberculatum on the cardiovascular.
Leaves obovate to lanceolate or linear, 51040 x 3610 mm, obtuse at the apex, cuneate or attenuate at the base, margin entire to crenate. Two new alkaloids, haplotubinone and haplotubine, were isolated from the aerial parts of haplophyllum tuberculatum together with the known lignan diphyllin. Skimmianine was identified by direct comparison with authentic material. The flora of saudi arabia is one of the richest biodiversity. Chemical composition, antimicrobial activity and antioxidative proprieties were assessed in airdried shoots of haplophyllum tuberculatum. In vitro antileishmanial and cytotoxicity activities of essential oils. Pdf alkaloids, coumarins and lignans from haplophyllum species. Juss is a perennial herb, belonging to the rutaceae family, native of north africa and other areas of the middle east. Effects of a methanolic extract of the plant haplophyllum. For more multimedia, look at haplophyllum on wikimedia commons. Chemical transformations and spectral evidence established its structure as 4o. All structured data from the file and property namespaces is available under the creative commons cc0 license. Juss rutaceae was analyzed by gas chromatographymass spectral gcms and c nmr spectroscopy. Cytotoxicity, mode of action and antibacterial activities of selected.
Tuberculatin, a new lignan apioside, was isolated from haplophyllum tuberculatum. Influence of haplophyllum tuberculatum on the cardiovascular system article in pharmaceutical biology 343. Essential oil article pdf available in journal of essential oilbearing plants jeop 173. This article is from bmc complementary and alternative medicine, volume. In vitro antileishmanial and cytotoxicity activities of. Pdf chemical composition and biological activity of. Antimicrobial and phytotoxic activities of secondary. It has a distinctive unpleasant odor, which makes it unattractive to grazing livestock. The structures of the new alkaloids were established by spectroscopic methods in conjunction with xray crystallographic analysis of 3. Flindersine, fagarine, skimmianine, evoxine and 33,3dimethylallyl43,3. General information about haplophyllum tuberculatum haytu southern mediterranean, western asia, india, saharan and eastern africa. Haplophyllum tuberculatum occurs in sandy desert, on a variety of soils, often on silt deposits, and also in dried watercourses, cultivated and ruderal localities, from sealevel up to 30 m altitude. Cheminform is a weekly abstracting service, delivering concise information at a glance that was extracted from about 100 leading journals.
Optical and electrochemical studies of silver nanoparticles biosynthesized by haplophyllum tuberculatum extract and their antibacterial activity in wastewater treatment. The essential oil of haplophyllum tuberculatumwas prepared by hydrodistillation of the fresh flowering aerial parts of the plant collected from saudi arabia. Leaf surface properties of the genus haplophyllum rutaceae. In this study and in order to contribute for the search of new natural drugs for leishmaniasis, the essential oils of h. Chemical composition, antibacterial and antifungal activities of the essential oil of haplophyllum tuberculatum from oman.
The medicinal plant haplophyllum tuberculatum is used by native people against malaria and parasitic infections. Perennial herb, sometimes somewhat woody at the base, up to c. Antimicrobial and phytotoxic activities of secondary metabolites from haplophyllum tuberculatum and chrysanthemum coronarium. Alkaloids from haplophyllum tuberculatum sciencedirect. Haplophyllum tuberculatum in global plants on jstor. Haplophyllum tuberculatum kheisa, mesaika, sazab, zeita in flora of qatar, with photos of the plant in its habitat. Optical and electrochemical studies of silver nanoparticles. Pdf the essential oil of haplophyllum tuberculatum was prepared by hydrodistillation of the fresh flowering aerial. Pdf essential oil of haplophyllum tuberculatum forssk. Micropropagation of haplophyllum tuberculatum, ochradenus baccatus, and salvia spinosa through axillary bud culture showed different morphogenic potentials depending on species type and ratio of 1naphthylacetic acid naa to 6benzylaminopurine bap supplemented in murashige and skoog ms culture medium. To quantify total phenols, flavonoids and to investigate the in vitro antioxidant\ud power of haplophyllum tuberculatum h. The plant is growing wild in the northern coast of egypt. Haplophyllum tuberculatum, belonging to the rutaceae family, is distributed in southeastern regions of iran, particularly in.
P hylogeny, morphology, and biogeography of haplophyllum. This species is accepted, and its native range is n. Chemical and biological activities of haplophyllum. The aerial part of this plant is used as laxative, to cure gastrointestinal affections, intermittent fevers, rheumatisms 11, malaria, gynecological disorders and renal disorders 12.
The aerial parts of haplophyllum tuberculatum collected in sudan have yielded the furoquinoline alkaloid skimmianine, the lignan justicidina, and 5,7,4. Leaf surface properties of the genus haplophyllum rutaceae in jordan mariam alkhatib and dawud aleisawi department of biological sciences, faculty of science, the university of jordan, amman, jordan corresponding author abstract introduction the genus haplophyllum has 68 species townsend, 1986, and reach maximum. Cytotoxicity, mode of action and antibacterial activities. Khattab 2 1botany and microbiology department, faculty of science, alexandria university, alexandria, egypt 2botany department, faculty of science, damanhour university, damanhour, egypt. Effects of a methanolic extract of the plant haplophyllum tuberculatum and of teflubenzuron on female reproduction in the migratory locust, locusta migratoria orthoptera.
Haplophyllum tuberculatum kheisa, mesaika, sazab, zeita in flora of qatar, with photos of the plant in its habitat home page picture archives flora of qatar rutaceae haplophyllum tuberculatum. This page was last edited on 15 november 2011, at 17. Composition of the essential oil of endemic haplophyllum. Haplophyllum tuberculatum journal of herbmed pharmacology. Haplophyllum about 70 species occurs from the mediterranean region to eastern siberia. Pharmacological importance of haplophyllum species grown in iraq.
Differential allelopathic effect of nine haplophyllum tuberculatum growth forms through germination bioassay salama m. Previous studies on the chemical compositions of the oils obtained from haplophyllum species growing in different countries showed that members of this genus possess essential oils with different compositions. Journal of ethnopharmacology 96 akademische druck 12, 107. International audiencethe chemical composition of the essential oil of haplophyllum tuberculatum forssk. Haplophyllum species are perennial herbs, sometimes low.
Digest alburtamani journal of nanomaterials and biostructures sks, fatope mo, marwah rg, onifade ak, alsaidi sh. The bioactive molecules of this plant play an important role in human health. Plants used for traditional medicine produce diverse and complex secondary metabolites exhibiting various medicinal properties. Townsend from the gilgitbaltistan province of pakistan. Pdf download buy article permissions and reprints abstract the aerial parts of haplophyllum tuberculatum collected in sudan have yielded the furoquinoline alkaloid skimmianine, the lignan justicidina, and 5,7,4. Files are available under licenses specified on their description page. The plant haplophyllum tuberculatum in sistan and baluchistan province is an important medicinal plant that has many medicinal properties.
The isolation scheme of the three alkaloids from h. Polyphenolic contents, antioxidant activities and uplcesims. Chemical composition of the essential oil of haplophyllum. To access a cheminform abstract of an article which was published elsewhere, please select a full text. Glycoperine a new alkaloid from haplophyllum perforatum. Polyphenolic contents, antioxidant activities and uplcesims analysis of haplophyllum tuberculatum a. Pharmacological importance of haplophyllum species grown. Antioxidant activity and chemical constituents of essential oil and. Biological activities of haplophyllum tuberculatum essential oil were screened. Institute of the chemistry of plant substances, academy of sciences of the uzbek ssr. Differential allelopathic effect of nine haplophyllum. Alkaloids, coumarins and lignans from haplophyllum species.
The chemical composition of the essential oil of haplophyllum tuberculatum forsskal a. Samples were subjected either to organic fractionated extraction hexane, chloroform and methanol or hydrodistillation for essential oil extraction. Acetone and methanol extracts of haplophyllum tuberculatum aerial parts showed better antioxidant activity. This page was last edited on 18 december 2019, at 01.298 1178 1363 1548 866 1271 372 292 299 641 692 312 602 1264 869 175 896 777 275 607 394 1172 631 1194 1316 534 787 1092 1223 694 926 241 113 697 533 521 551 484 54 632 1165 220 794